The default assumption of the damage on the below Innate Attack lines is to represent most weapon's maximum damage dealing capability. Thus, this can handle anything with a minimum ST of 23 or less. This should be more than sufficient for most non-giant-sized weapons. For larger weapons, a customized version of this spell (requiring the appropriate research and expense) with a higher damage potential is required.

Affliction [68] 
    Advantage [+578%] 
        Innate Attack (Crushing) 10d+10 [3.9] 
        Innate Attack (Cutting) 10d+10 [5.46] 
        Innate Attack (Impaling) 10d+10 [31.2] 
        Innate Attack (Small Piercing) 10d+10 [2.34] 
        Innate Attack (Piercing) 10d+10 [3.9] 
        Innate Attack (Large Piercing) 10d+10 [4.68] 
        Innate Attack (Huge Piercing) 10d+10 [6.24] 
        Armor Divisor (2) [+30%] 
            Must Be Wielded (Anyone can use) [-30%] 
            Magical [-10%] 
        No Base [-100%] 
        Alternate Ability [x1/5] 
            On all but Impaling 
    Malediction (As Regular Spell) [+100%] 
    Based on Activation Roll [+5%] 
    Melee Attack (Reach C, No Parry) [-35%] 
    Only Works on Weapons [-40%] 
    Magical [-10%] 
    Spell Components [-20%] 
        Must say "penetrate" in Latin 
        Must gesture with hands 
Level 2 [126] 
    Increase Armor Divisor to (3) [+577%] 
Level 3 [184] 
    Increase Armor Divisor to (5) [+577%] 
Level 4 [241] 
    Increase Armor Divisor to (10) [+577%] 
Level 5 [356] 
    Replace Armor Divisor with Cosmic (Irresistible Attack) [+1155%] 
Projectile Option [+1] 
    Area Effect (2 Yard Radius) [+50%] 
    Add Only Works on a Handful [-30%] 
    Change Only Works on Weapons to Only Works on Projectiles [-10%] 
        Anything that can be thrown or can be fired from a weapon 
        Rocks, darts, arrows, etc. 
        Throwing axes don't count; they're also melee weapons